Slay the Spire 2 Wiki

Card

Misery

Deal 7 damage. Apply any debuffs on the enemy to ALL other enemies.

Misery is a rare Necrobinder attack costing 0 Energy that deals 7 damage and spreads any debuffs on the target to ALL other enemies. At zero cost, it provides efficient damage and unparalleled debuff proliferation in multi-enemy fights.

Misery is the perfect follow-up after Deathbringer applies Doom and Weak to all enemies, compounding the debuffs further. Putrefy's Weak and Vulnerable spread to all targets through Misery. Enfeebling Touch's massive Strength reduction becomes devastating when Misery copies it to every enemy on the field.

In Necrobinder Doom builds, Misery turns single-target Doom application into AoE execution setup. Against bosses that summon minions like Doormaker and Ceremonial Beast, applying heavy Doom to one target and then spreading it with Misery sets up End of Days to execute the entire field. The 0-cost makes it easy to weave into any turn's card sequence.

Details

Card TypeAttack
Cost0
RarityRare
TargetSingle-Enemy
Effect TextDeal 7 Damage. Apply Any Debuffs On The Enemy To ALL Other Enemies.

Character

NoindexYes
In GameConfirmed

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Quick Facts

Type
Card
Confidence
Medium
Verified
Mar 12, 2026