Fruit Juice

Fruit Juice permanently increases your maximum HP when consumed, providing a lasting benefit that persists beyond the current combat. Unlike healing potions that restore current HP, Fruit Juice raises your ceiling, making you more resilient for every future encounter in the run.

Drink Fruit Juice as soon as you obtain it since its max HP benefit applies to every subsequent fight. It is particularly valuable before challenging boss fights against Ceremonial Beast or The Insatiable, where the extra maximum HP provides a larger buffer against their punishing attack patterns.

Ironclad benefits most from Fruit Juice alongside Feed, which also raises max HP on kills, creating a strategy focused on growing your health pool throughout the run. Burning Blood heals a percentage at end of combat, so higher max HP increases that healing. Reaper's lifesteal also benefits from a higher HP ceiling. Necrobinder appreciates the extra HP to offset self-damage from Forbidden Grimoire. Sacred Bark doubles the max HP gain, and Toy Ornithopter adds healing. Sozu prevents future potions, so drink Fruit Juice immediately if you carry that relic.