Slay the Spire 2 Wiki

Potion

Blessing of the Forge

Upgrade all cards in your Hand for the rest of combat.

Blessing of the Forge upgrades a card in your hand for the rest of combat, providing a permanent enhancement without visiting a rest site. This potion essentially gives you a free campfire upgrade at the moment you need it most, turning a good card into a great one mid-fight.

This potion is best saved for long boss fights like the Soul Fysh encounter where upgraded cards compound their value over many turns. It is also strong against Kin Priest, where the incremental advantage of an upgraded key card can help you sustain through the fight's demanding pacing.

Ironclad should target Demon Form for upgrade, turning it into an even faster Strength engine, or upgrade Feed to gain more max HP per kill. Necrobinder benefits from upgrading Necro Mastery or Forbidden Grimoire for enhanced summoning power. The Regent can upgrade Venerate for stronger scaling. Sozu prevents potion acquisition, so if you have Blessing of the Forge, use it rather than risk losing it. Toy Ornithopter provides a small heal on use as a bonus.

Details

Potion RarityUncommon
EffectUpgrade All Cards In Your Hand For The Rest Of Combat.
NoindexYes
In GameConfirmed

Guides & Articles

Quick Facts

Type
Potion
Confidence
High
Verified
Mar 12, 2026

Sources

slaythespire.wiki.gg/wiki/Potions_List_(Slay_the_Spire_2)