Slay the Spire 2 Wiki

Card

Serpent Form

Whenever you play a card, deal 4 damage to a random enemy.

Serpent Form is a 3-cost rare Power card for the Silent that grants 1 Intangible at the start of each turn for the rest of the fight. Unlike Wraith Form which provides 2 turns of Intangible with a penalty, Serpent Form provides permanent Intangible with no downside beyond the steep 3-energy cost. Every single turn, ALL damage is reduced to 1 per hit.

Serpent Form eliminates the need for most Block cards, but pairs with Footwork for when you want supplemental Block on top of Intangible. Afterimage still provides useful chip Block for each card played. Noxious Fumes and Poison cards become the ideal damage strategy since you can ignore defense entirely and focus on passive damage. Accelerant helps afford the 3-energy cost more easily.

Silent players should pick Serpent Form as a game-ending defensive Power that trivializes virtually every fight, including bosses like Doormaker and Test Subject #C10. The 3-energy cost means you need energy generation to play it and still do anything productive on that turn. Pair it with Poison-based offense like Noxious Fumes and Outbreak so you can win without needing Attack energy.

Details

Card TypePower
Cost3
RarityRare
TargetAll-Enemies
Effect TextWhenever You Play A Card, Deal 4 Damage To A Random Enemy.

Character

NoindexNo
In GameConfirmed

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Quick Facts

Type
Card
Confidence
High
Verified
Mar 12, 2026