Ghost in a Jar

Ghost in a Jar grants Intangible for one turn, reducing all damage taken to just one per hit. This is one of the most powerful defensive effects in the game, trivializing even the most devastating enemy attacks for an entire turn regardless of how many hits or how much damage they deal.

Ghost in a Jar is invaluable against multi-hit boss attacks from Ceremonial Beast and The Insatiable, where Intangible reduces each hit to one damage instead of taking the full brunt. Save it for Lagavulin Matriarch's highest damage turns to completely negate her strongest attacks.

Silent synergizes best with Ghost in a Jar since Wraith Form provides the same effect as a card, and Nightmare can duplicate Wraith Form for extended Intangible. Afterimage provides additional Block on top of Intangible for near-total immunity. Ironclad can use the free turn to play Demon Form or Offering without worrying about incoming damage. Sacred Bark extends the Intangible duration, and Toy Ornithopter heals when using the potion. Sozu makes this potion even more precious since you will not find replacements.