Slay the Spire 2 Wiki

Card

Hemokinesis

Lose 2 HP. Deal 14 damage.

Hemokinesis is a 1-cost Uncommon Attack card for the Ironclad that causes you to lose 2 HP and deal 14 damage. The high damage-to-cost ratio makes it one of the most energy-efficient damage cards, with the HP loss being the Ironclad's signature tradeoff.

Hemokinesis triggers Rupture for Strength gain and Crimson Mantle for both Strength and Block. Inferno deals AoE damage whenever you lose HP, adding splash damage to the single-target hit. The Ironclad's Burning Blood relic helps offset the 2 HP cost between combats. Pair with Inflame or Demon Form to push the damage even higher. Spite grows in damage based on total HP lost, benefiting from Hemokinesis's HP payment.

Hemokinesis is a solid damage card for any Ironclad deck, with extra value in self-damage builds. Pick it as an efficient damage source, especially with Rupture or Crimson Mantle. Against Knowledge Demon, the high damage per energy helps end the fight quickly. The 2 HP cost is negligible in most situations. Against Vantom, where efficient damage matters, Hemokinesis is one of the Ironclad's best options.

Details

Card TypeAttack
Cost1
RarityUncommon
TargetSingle-Enemy
Effect TextLose 2 HP. Deal 14 Damage.

Character

NoindexNo
In GameConfirmed

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Quick Facts

Type
Card
Confidence
Medium
Verified
Mar 12, 2026