Weak Potion

Weak Potion applies the Weak debuff to an enemy, reducing their attack damage by 25 percent for several turns. This potion serves as a reliable defensive tool that requires no energy, letting you mitigate incoming damage while spending your energy on offense or scaling.

Weak Potion is essential against heavy hitters like Lagavulin Matriarch, where reducing attack damage keeps you alive through sustained pressure. It is also valuable in the Kaiser Crab fight to reduce the impact of its powerful strikes while you chip through its defenses.

Ironclad benefits from Weak Potion when paired with Rupture strategies, since taking less damage means more controlled self-harm. Silent has natural Weak application through cards but appreciates the potion for turn-one safety before Noxious Fumes or Malaise come online. Defect can use it alongside Biased Cognition turns when defense is thin. Sacred Bark extends the Weak duration for prolonged damage reduction, and White Beast Statue helps you find more potions like this throughout your run.